Anti-inflammatory evaluation of ethanolic extract of leaves of Holoptelea integrifolia, Planch
نویسنده
چکیده
The purpose of the present study was to investigate the anti-inflammatory properties of ethanolic extract of the leaves of Holoptelea integrifolia Planch. (EHI). The different anti-inflammatory models were used. The EHI at dose (250 and 500mg/kg p.o) was given to observe percentage inhibition of paw oedema which were comparable with indomethacin (10mg/kg p.o) used as a reference drug. The extract (500mgkg b.w) exhibited maximum anti-inflammatory effect with carrageenan, dextran, histamine, serotonin and cotton pellet method respectively. A significant percentage inhibition of paw oedema by the EHI as compared to standard drug suggests its usefulness in acute and chronic anti-inflammatory models.
منابع مشابه
Studies on anti-inflammatory effect of aqueous extract of leaves of Holoptelea integrifolia, Planch. in rats
OBJECTIVES The purpose of the present study was to investigate the anti-inflammatory properties of aqueous extract of the leaves of H. integrifolia, Planch. MATERIALS AND METHODS The hind paw edema was produced in rats by subplanter injection of carageenan. The aqueous extract of H. integrifolia, Planch. (AHI) at dose (250 and 500 mg/kg p.o) was given to observe % inhibition of paw edema whic...
متن کاملThe Wonders of a Medicinal Tree: Holoptelea Integrifolia (roxb.) Planch
In this busy era of herbal sciences, extensive study is being carried out on numerous plants to find novel drugs among which Holoptelea integrifolia Roxb. (Indian Elm) tree is just one of them. The age old knowledge ethnopharmacological significance, especially the stem, bark and leaves is well recognized in several Siddha, Ayurvedic, Unani literature. The plant parts are extensively used for i...
متن کاملAntioxidant, Heavy Metals and Elemental Analysis of Holoptelea integrifolia Planch
The ethanol crude extract of stem bark of Holoptelea integrifolia Planch. traditionally used in Indian system of medicine was screened for its antioxidant activity using α-tocopherol as standard antioxidant. The free radical scavenging potential of the extract was evaluated by two different antioxidant methods; ferric thiocyanate and thiobarbituric acid method. The ethanol extract was found to ...
متن کاملPhytochemical Screening of some compounds from plant leaf extracts of Holoptelea integrifolia (Planch.) and Celestrus emarginata (Grah.) used by Gondu tribes at Adilabad District, Andhrapradesh, India
Phytochemicals are secondary metabolites produced by all plants in which some has medicinal uses. The phytochemical analysis of leaf extracts in aqueous, methanol, acetone, petroleum ether and chloroform extracts of indigenous medicinally important plants of Holoptelea integrifolia and Celestrus emarginata were investigated. The phytochemical analysis revealed the presence of alkaloids, saponin...
متن کاملAnalgesic activity of various extracts of Holoptelea integrifolia (Roxb.) Planch leaves.
The various extracts of leaves Holoptelea integrifolia (Ulmaceae) were investigated for analgesic activity in mice by tail flick method. The fresh plant leaves of H. integrifolia were collected, dried, cleaned, weighed and chopped into small pieces and percolated in ethanol. The fractionation of crude extract, followed by the addition of distilled water, ethyl acetate and n-butanol to an aqueou...
متن کامل